Last lear 53 people were killed in Hawaii due to drunk driving.
One out of 12 drivers in the U.S. drives drunk.
When you consider the number of people out on a three day holiday, the combination can be deadly.
Honolulu Police are stepping up enforcement to keep drunk drivers off the road.
Overnight a massive DUI roadblock on the Ala Wai stopped hundreds of cars.
The effort continued into the afternoon over at Ala Moana Beach Park.
"It's not illegal to drink, but it is illegal to drink and then drive," said Major Danton Nakama of the Honolulu Police Department.
Supporters with Mother's Against Drunk Driving lined the roadway reaching out to drivers.
"We're out here to remind drivers don't drink don't drive, don't kill someone don't kill yourself," said Jennifer Dotson of Mothers Against Drunk Driving.
HPD says as of yesterday they have conducted 256 DUI roadblocks on Oahu - resulting in 2,478 arrests as of July 31.
So far this year 38-people were killed in car crashes on Oahu - 8 involving alcohol. Another 7 people were critically injured in alcohol related crashes.
"We hear too often, too often a life is lost because of a Drunk driver, because of a fatal choice to drink and drive and get behind the wheel," said Dotson. "Needless, senseless tragedies that can be avoided if people just don't drink and drive."
Boaters are also being urged to stay sober while celebrating this weekend.
The Coast Guard says alcohol contributes to more than half of boating mishaps --- and operating a boat under the influence of alcohol is illegal.